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Prof. Dr. Jochen Staiger

Prof. Dr. Bernhard Reuss

Gabriele Schmidt

Dr. rer. nat. Julien Guy

Dr. rer. nat. Martin Möck

Dr. med. Rebeka Andrea Palicz

Dr. Stefan Pommer

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Dr. rer. nat. Mirko Witte

Merve Özgür Erat

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Harun Akkoyun

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Philipp Kolligs

Lukas Müller

Flore Schork

Sophia Heidenreich

Ima Mansori

Leander Matthes

Paul Molis

Sandra Heinzl

Sabrina Hübner

Patricia Sprysch

Pavel Truschow

Dr. rer. nat. Csaba Dávid

Dr. rer. nat. Alvar Prönneke

PD Dr. Michael Rickmann

Dr. Marcel Ruiz Mejias

Dr. rer. nat. Dirk Schubert

Dr. Godwin Sokpor

Dr. rer. nat. Nidhi Subhashini

Dr. rer. nat. Tran Tuoc

Dr. med. Robin Wagener

Dr. rer. nat. Yuanbin Xie

Dr. rer. nat. Xiaojuan Zhou

Eman Abbas

Weilin Chen

Michael Feyerabend

Georg Hafner

Kamila Kiszka

Anouk Meeuwissen

Nieves Mingo Moreno

Ramanathan Narayanan

Huong Nguyen

Pauline Antonie Ulmke

Florian Walker

Khatuna Aslanishvili

Christina Bachmann

Simon Badura

Thore Behrendt

Jürgen Delchmann

Esther Alexandra Dockhorn

Tatjana Fischer

Anna Garcia Galera

Kristina Glöckner

Janis Hülsemann

Dilbrin Khelo

Stephen Olt

Bettina Pater

Alina Rüppel

Alexandra Sachkova

Bianca Scheuer

Lisa Thiecke

Joris Brehmer

Dennis Dalügge

Julia Dziubek

Ricardo Castro Hernandez

Fernando Gonzalez Ibanez

Christin Korb

Anette Mertens

Megha Patwa

Adrián Villalobos

Simon Weiler

Maxim Wintergoller

Nicolas Zdun

Anna Dudek

Heike Faust

Sabrina Heide

Ansgar Jahn

Linh Pham


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Michael

Feyerabend


Last Name: Feyerabend Position: PhD Student
First Name: Michael Location: Göttingen
Academic Title: Tel.:

Publications

Curriculum Vitae


Publications

2019

Pathway-, layer- and cell-type-specific thalamic input to mouse barrel cortex.
Sermet BS, Truschow P, Feyerabend M, Mayrhofer JM, Oram TB, Yizhar O, Staiger JF, Petersen CCH.
eLife 2019;8:e52665 , 2019.
abstract link

Mouse primary somatosensory barrel cortex (wS1) processes whisker sensory information, receiving input from two distinct thalamic nuclei. The first-order ventral posterior medial (VPM) somatosensory thalamic nucleus most densely innervates layer 4 (L4) barrels, whereas the higher-order posterior thalamic nucleus (medial part, POm) most densely innervates L1 and L5A. We optogenetically stimulated VPM or POm axons, and recorded evoked excitatory postsynaptic potentials (EPSPs) in different cell-types across cortical layers in wS1. We found that excitatory neurons and parvalbumin-expressing inhibitory neurons received the largest EPSPs, dominated by VPM input to L4 and POm input to L5A. In contrast, somatostatin-expressing inhibitory neurons received very little input from either pathway in any layer. Vasoactive intestinal peptide-expressing inhibitory neurons received an intermediate level of excitatory input with less apparent layer-specificity. Our data help understand how wS1 neocortical microcircuits might process and integrate sensory and higher-order inputs.

2016

Parvalbumin- and vasoactive intestinal polypeptide-expressing neocortical interneurons impose differential inhibition on Martinotti cells.
Walker F, Möck M, Feyerabend M, Guy J, Wagener RJ, Schubert D, Staiger JF, Witte M.
Nature Comunications 7:13664 (DOI: 10.1038/ncomms13664, 2016.
abstract link

Disinhibition of cortical excitatory cell gate information flow through and between corticalcolumns. The major contribution of Martinotti cells (MC) is providing dendritic inhibition toexcitatory neurons and therefore they are a main component of disinhibitory connections.Here we show by means of optogenetics that MC in layers II/III of the mouse primarysomatosensory cortex are inhibited by both parvalbumin (PV)- and vasoactive intestinalpolypeptide (VIP)-expressing cells. Paired recordings revealed stronger synaptic inputonto MC from PV cells than from VIP cells. Moreover, PV cell input showed frequencyindependentdepression, whereas VIP cell input facilitated at high frequencies. Thesedifferences in the properties of the two unitary connections enable disinhibition with distincttemporal features.



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